modafinil dosage - An Overview
carbamazepine will reduce the extent or result of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
Desk 1 presents the adverse reactions that transpired in a price of one% or even more and ended up additional Recurrent in PROVIGIL-taken care of clients than in placebo-handled individuals during the placebo-controlled clinical trials.
The encouraged dosage of PROVIGIL for people with narcolepsy or OSA is two hundred mg taken orally after every day as only one dose in the morning.
Just about every capsule-formed, white to off white, scored tablet is debossed with “PROVIGIL†on just one facet and “200 MG†on another.
modafinil will increase amounts of eluxadoline by impacting hepatic enzyme CYP2C19 metabolism. Use Warning/Check. For a precautionary measure as a result of incomplete information on the metabolism of eluxadoline, use caution when coadministered with solid CYP2C19 inhibitors.
modafinil will lessen the level or impact of pacritinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
Doses around 400 mg/working day, presented as an individual dose, happen to be well tolerated, but there's no regular evidence this dose confers more reward further than that on the 200 mg/working day dose
Geriatric Use: In aged clients, modafinil and metabolite elimination may very well be diminished, so consider using decrease doses and intently observe people.
nelfinavir will improve the degree or effect of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
Stiripentol is a CYP3A4 inhibitor and inducer. Keep track of CYP3A4 substrates coadministered with stiripentol for improved or reduced effects. CYP3A4 substrates could call for dosage adjustment.
Danger of pores and skin reactions (eg SJS, harmful necrolysis, and drug rash with eosinophilia and systemic signs and symptoms); discontinue if rash or other hypersensitivity reactions occur
It's not known whether this drugs will harm an unborn infant. Convey to your health care provider Should you be Expecting or strategy to become Expecting.
 advised for people today just beginning with modafinil. It may cause read more panic, insomnia, and various Unintended effects. If you wish to do that dose, even In case you have a larger than regular Develop, it is best to often Establish the dose up little by little from possibly 50 mg or a hundred mg.
From postmarketing practical experience, there are studies of fatal overdoses involving modafinil alone or together with other medications. Signs most often accompanying PROVIGIL